摘要
目的 :比较国产丁螺环酮和阿普唑仑治疗广泛性焦虑的疗效和不良反应。 方法 :对 78例广泛性焦虑按照就医顺序分为两组 ,分别服用丁螺环酮 (38例 )和阿普唑仑 (4 0例 )。疗程 6周。于治疗前及治疗第 1、2、4、6周末进行汉密尔顿焦虑量表 (HAMA)及副反应量表 (TESS)评定疗效和不良反应。 结果 :丁螺环酮和阿普唑仑的疗效相仿 ,丁螺环酮的不良反应少且轻微 ,无过度镇静和肌肉松弛作用 ,不产生药物依赖。 结论 :丁螺环酮是治疗广泛性焦虑较为理想的药物。
Objective:To evaluate the efficacy and side effects of bisprone and alprazolam in the trearment of generalized anxiety disorder. Method:78 patients were assigned to bisprone group (n=38) and alprazolam group (n=40) respectively for 6 weeks.The efficacy and side effects were evaluated by HAMA and TESS before and after 1, 2,3,4 and 6 weeks. Results:The efficacy of bisprone and alprazolam had no significant difference,but bisprone had fewer side effects. Conclusion:Bisprone is an effective and safe medicine in the treatment of generalized anxiety disorder.
出处
《临床精神医学杂志》
2004年第4期239-240,共2页
Journal of Clinical Psychiatry
关键词
丁螺环酮
阿普唑仑
广泛性焦虑
Bisprone
Alprazolam
Generalized anxiety disorder
