摘要
目的 :探讨冠心病患者外周血红蛋白含量 (Hb)与急性冠状动脉综合征 (ACS)的相关性。方法 :应用美国库尔特JT血球计数器测定Hb含量 ,结合冠状动脉造影 (冠脉造影 )及超声心动图检查 ,观察 2 86例冠心病患者Hb含量及其与冠状动脉硬化及ACS的相关性。结果 :冠心病患者外周血中Hb含量较正常对照组显著增加 (P <0 0 5 ) ,其中ACS组 (急性心肌梗死及不稳定型心绞痛 )Hb含量较正常对照组增加更明显。四分位法研究ACS组Hb含量位于最高 1 4位者较最低 1 4位者显著增加 (P <0 0 5 )。ACS组Hb含量位于最高 1 4位者较稳定型心绞痛 (SAP)组显著增加 (P <0 0 5 )。Hb含量位于最高 1 4位者发生ACS者较Hb含量位于最低 1 4位者显著增加 (P <0 0 5 )。冠状动脉造影显示ACS组冠状动脉狭窄≥ 95 %及冠状动脉闭塞病变的发生率显著高于SAP组 ,冠状动脉闭塞组其Hb含量 (15 0 92± 12 80 )g L显著高于无冠状动脉闭塞组 (139 98± 13 11)g L(P <0 0 5 )。结论 :ACS患者中血红蛋白含量较高。
Objective: To investigate the relationship between hemoglobin(Hb) and acute coronary syndrom. Method: 286 CHD Patients,average 63.16±12.21 years,male 182 cases and female 104 cases,were examined Hb contentsand the atherosclerotic changes were quantified by coronary arteriography.Result:the Hb is significantly increased in CHD patients compared with control group,and increased much more in acute coronary syndrome (acute myocaridal infarction and unstable angina pectoris).ACS in the highest quartile of Hb group is significantly increased in comparison with the lowest quartile of Hb group.A large proportion of ACSs occurred among patients in the highest quintile.ACS in highest quartile of Hb group is significantly increased in comparison with the stable angina pectoris (SAP).Correlation analysis showed that Hb correlated positively to the level of coronany artery stenosis.Conclusion:These findings show that Hb may is significantly increased in ACS.
出处
《心肺血管病杂志》
CAS
2004年第2期84-87,共4页
Journal of Cardiovascular and Pulmonary Diseases
