摘要
目的 探讨脑卒中后癫痫的临床特征及发病机制。方法 对 1 86 0例脑卒中患者中的1 6 0例继发癫痫者的临床资料进行回顾性分析。结果 卒中后癫痫总发生率为 8.6 % ,其中早发型癫痫占 6 4 % ,迟发型癫痫占 36 %。早发型癫痫多见于脑出血 ,而迟发型癫痫多见于脑梗死。卒中后癫痫的发生率因病灶部位 (皮质 /皮质下 )的不同存在显著性差异。皮质病灶中 ,位于额叶、颞叶、顶叶者好发癫痫。皮质下区病灶在基底节、内囊者易发生癫痫。结论 脑卒中后癫痫以早发型为多 ,早期癫痫多见于脑出血 ,而迟发型癫痫多见于脑梗死。病灶位于皮质者发生癫痫的危险性高 。
Objective To discuss the clinic manifestation and the mechanism of the epilepsy after stroke. Methods We reviewed and analyzed 160 patients having one or more epileptic seizures among 1860 hospitalized patients with evidence of completed stroke. Results The incidence of epilepsy after stroke is 8.6%. Among it, the patients with early seizure occupied 64%, while those with late seizure accounted for 36%. Early seizure was also commonly found after intra-cerebral hemorrhage, while late seizure was commonly found after cerebral infarction. The incidence varied with the focus location (cortical/sub-cortical). It was easy to have epileptic seizures when the focus located frontal lobe, temporal lobe and parietal lobe among cortical focus, and when the focus lay in basal ganglia and internal capsule among sub-cortical focus. Conclusions Early seizure occurred more frequently after stroke. It was also commonly found after intra-cerebral hemorrhage, while late seizure was commonly found after cerebral infarction. The Strokes with cortical involvement were found to be more commonly associated with seizures. But sub-cortical structures also played a significant role in the genesis of epileptic seizures.
出处
《神经疾病与精神卫生》
2004年第3期190-191,共2页
Journal of Neuroscience and Mental Health
