摘要
本文介绍用交流示波极谱滴定法测定吡哌酸的含量。在HCl-NaAc缓冲溶液中,加入过量的Na-TPB与吡哌酸作用生成沉淀,过滤后用亚铊标准溶液滴定滤液中过量的TPB,由交流示波极谱图上TPB的切口消失指示终点。本法操作简便,终点直观,应用于原料药样品的测定,并与药典法相对照,结果基本吻合。
The determination of pipemidic acid(PPA)by A. C. oscillopolarographic titration is reported. The excess of sodium tetraphenylborate (Na-TPB) is added to precipitate PPA in HCl-NaAc buffer solution. After filtering off part of the mixture, the excess of TPB in the filtrate is titrated with thallous nitrate standard solution. The disappearance of the incision of TPB on dE/d/ = f(E) curve is used to indicate the end point of titration. The method is simple and rapid. The end point of titration is sensitive. The method has been applied to the determination of PPA with satisfactory results.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
1993年第12期1404-1406,共3页
Chinese Journal of Analytical Chemistry
关键词
示波极谱
滴定
吡哌酸
四苯硼钠
Oscillopoiarographic titration. Alternating carrent polarography,Pipemidic acid, Sodium te-traphenylborate.
