摘要
目的 评估深低温保存血小板在临床输注的有效性与安全性。方法 对 1,2 94例输注患者进行深低温保存血小板输注研究。其中各类型白血病 3 2 6例 ,再生障碍性贫血 167例 ,恶性肿瘤放疗及化疗及其它原因所致的血小板减少 2 5 4例 ,术前、术中、术后输注血小板 5 47例。观察输注前、后 1h出血时间 ,输后伤口停止出血时间、血小板计数、体表瘀斑消散情况、不良反应等各项指标。结果 输注深低温保存的血小板具有升高血小板作用和显著的止血效果 ,内科输注总有效率 89 8% ,外科输注总有效率95 1% ,无明显副作用发生。结论深低温保存血小板在内、外科出血患者应用均安全。
Objective To estimate efficacy and safety of transfusion of cryopreserved platelets in different patients. Methods 1294 patients in recent years with hemorrhage or risk of hemorrhage, who received transfusion of cryopreserved platelets,were included in this study. The following indexes were recorded:bleeding time before and one hour after transfusion, the persistent time of blood oozing from wound after transfusion, platelet count before and one hour after transfusion, change of subcutaneous petechia, and complications of blood transfusion. Results Cryopreserved platelets could bring about the immediate cessation of blood oozing from the wound,and elevation of peripheral blood platelet count without distinct complications of blood transfusion. The total effective rates of 747 medical cases and 547 surgical cases were 89.8% and 95.1% respectively. Conclusion It is safe and efficacious to transfuse cryopreserved platelets in medical and surgical patients.
出处
《中国医师杂志》
CAS
2004年第8期1046-1048,共3页
Journal of Chinese Physician
关键词
深低温保存
血小板
输血治疗
贫血
适应证
Platelets transfusion
Cryopreservation
Hemorrhage/Hemostasia
