摘要
【目的】 了解神经管缺陷的基本分布情况 ,分析其环境及行为危险因素。 【方法】 以入户或电话采访的方式对病例和对照的双亲进行调查 ,获取他们是否暴露于相关因素的资料 ,再对暴露因素进行Logistic回归分析。 【结果】 神经管缺陷的发生率为 9.87/ 10 4,无脑儿、脑积水占的比例较高 ,居住地在农村占的比例比城市略高。母亲营养状况不佳、有妊娠合并症、孕期发热和父亲酗酒与神经管缺陷的发生呈正相关。 【结论】 为减少神经管缺陷的发生 ,育龄妇女除了增补叶酸以外 。
To understand the basic distribution of neural tube defects and analyze the environment risk factors. It was investigated the parents of casese and controls by phone or visitation and obtained the material whether they have contacted the relevant risk factor or not, then used the logistic regression analysis to analyze these material and risk factors. The incidence of neural tube defects was 0.987‰. The case living in country were more than that living in city. The result of logistic regression analysis telled us that mather's malnutrition, hyperemesis gravidarum ,fever and father alcoholism were positive relation to neural tube defects. [Conclusions] In order to reduce the incidence of neural tube defects ,child bearing aged women not only increase the folic acid intake but also avoid to contact circumstance and action risk factors.
出处
《中国儿童保健杂志》
CAS
2004年第1期12-14,共3页
Chinese Journal of Child Health Care
基金
广西自治区卫生厅计划项目 (990 6)
