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对世界银行贷款卫生九项目4个省HIV检测能力和初筛实验室网络建设分析评估 被引量:6

Evaluation of HIV testing ability and laboratory networks in four provinces of World Bank Loan Project Health Ⅸ
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摘要 目的 调查了解世界银行贷款卫生九 (卫九 )项目广西、福建、山西、新疆 4个省 (自治区 )艾滋病病毒(HIV)检测能力和实验室网络的现况 ;项目启动以来 ,中国疾病预防控制中心 (CDC)性病艾滋病预防控制中心国家HIV参比实验室举办培训班起的作用 ;根据疫情发展的需要 ,目前是否能满足需求。方法 采用现场调研指导和问卷调查相结合方法进行分析评估。结果  (1)覆盖面 :37个地区 (州、市 )、5 8个县 (区、市 ) ,占 4个省总人口的35 5 %。 (2 )HIV检测实验室网络建设 :已验收批准 198个HIV初筛实验室 ,比 1999年项目开始前增长 1 75倍。(3) 4个省共 10 3人次参加全国HIV检测专业培训 ,提高了人员的素质 ;积极组织订购仪器设备 ,目前总金额已达 532 9 0 1万元。近 4年合计HIV检测数 4 119935份 ,约为 1987~ 1998年 12年检测数的 1 4 4倍 ;报告阳性 9981例 ,是 1987~ 1998年报告阳性数的 3 0 3倍。 (4 )进口第 3代酶联免疫吸附试验 (ELISA)试剂和国产试剂复测 16 35份HIV抗体初筛阳性标本 ,S/CO均≥ 6者为 14 93份 ,两种试剂S/CO均 <6者为 2 4份 ,一致率为 92 8% (15 17/ 16 35 )。结论 项目启动 3年来 ,提高了省级CDCHIV确认实验室的业务水平和检测能力 ,项目 Objective To evaluate the current situation of HIV testing ability and laboratory networks in the 4 World Bank project provinces and the effect of training courses held by the National AIDS Reference Laboratory since the inception of the project,and also to identify whether the demands could be met with the development of current epidemic trends.Methods The evaluation was conducted by on-the-spot investigation of the laboratories involved in combination with interviews by questionnaires.Result (1)Coverage:A total of 37 districts(cities)and 58 counties(cities)covering,35.5% of the whole population in the 4 provinces were evaluated.(2)HIV testing laboratory network construction:A total of 198 HIV laboratories for primary screening were assessed and approved,and the number increased by 175% compared with that before the project.(3)A total of 103 person-time participated in the national training on HIV/AIDS testing with their professional skills considerably improved.The purchase of related instruments were properly arranged with a sum up to 53.29 million yuan.There were altogether 4,119,935 HIV tests performed in the recent 4 years,which was 1.44 times as high as the total number of tests performed in the past 12 years from 1987 to 1998.Altogether,9,981 positive cases were reported,i.e. an increase by 3.03 times.(4)In parallel testing of the 1*!635 screening positive samples by imported and home-made reagents,1*!493 samples were both S/CO≥6,while 24 samples were both S/CO≤6,and the consistency rate for the two reagents was 92.8%(1*!517/ 1*!635). Conclusion Since the initiation of the project,the HIV confirmatory central laboratories have improved their professional skills and testing ability,and the construction of the laboratory networks in the four project provinces has progressed greatly.By the end of 2002,the number of HIV testing laboratories has increased by 1.75 times.Parallel testing for the complementary method of epidemic reporting provided scientific base for its formulotion and disseminati
作者 蒋岩 邢玉兰
出处 《中国艾滋病性病》 CAS 2004年第3期159-162,共4页 Chinese Journal of Aids & STD
基金 世界银行卫生九项目艾滋病性病预防与控制子项目资助
关键词 艾滋病病毒 检测能力 实验室网络 补充方法 评估 HIV Testing ability Laboratory networks Complementary method Evaluation
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  • 2Urassa W,Godoy K,Killewo J,et al.The accuracy of an alternative confirmatory strategy for detection of antibodies to HIV-1:experience from a regional laboratory in Kagera,Tanzania[J].J Clin Virol.1999,14(1):25-29. 被引量:1
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