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喉癌中尿激酶型纤溶酶原激活剂的表达与肿瘤侵袭转移的关系 被引量:2

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摘要 尿激酶型纤溶酶原激活剂(urokinase-type plasminogen activator,uPA)和它的细胞表面特异受体(urokinase-type plasminogen activator receptor,uPAR)相结合,提高细胞表面范围纤溶酶的活动,在肿瘤侵袭和转移过程中起着关键作用,Ⅰ型纤溶酶原激活剂抑制剂(plasminogen activator inhibitor type-1,PAI-1)是uPA的主要抑制剂,调节uPA的活动[1].本实验应用免疫组织化学染色方法分析uPA系统各成分在声门上型喉癌组织中的表达和分布.
出处 《中华耳鼻咽喉科杂志》 CSCD 北大核心 2004年第7期439-440,共2页 Chinese Journal of Otorhinolaryngology
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同被引文献26

  • 1王大力,王铁.uPA及nm23-H1蛋白表达与喉鳞癌侵袭转移的关系[J].中国耳鼻咽喉颅底外科杂志,2005,11(4):221-224. 被引量:1
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