摘要
目的 观察降纤酶对不稳定型心绞痛 (UAP)患者的血流变特性及体外模拟血栓指数的影响。方法 选择符合UAP诊断标准的 70例患者 ,用降纤酶 1 0U静滴 ,每日一次 ,连用 5d ,观察治疗前后低、中、高切变率的血液流变特性指标及体外模拟血栓指数的变化。结果 治疗后低、中切变率下全血粘度及全血还原粘度、红细胞聚集指数、毛细管血浆粘度、血浆纤维蛋白原浓度、体外模拟血栓长度、湿重与血栓指数Q值均较治疗前明显降低。结论 治疗后降纤酶通过降低血纤维蛋白原浓度 ,降低全血粘度、血浆粘度及红细胞聚集性来改善血液流变特性异常 ,增加纤溶活性 ,抗栓 ,减少血栓形成 。
Objective To evaluate the effects of defibrase in improving the hemorheological properties for patients with unstable angina pectoris(UAP).Methods Defibrase was used to treat 70 of patients with UAP ,with the dose of 10U every day iv drop, qd, five days. Results After treatmeat the levels of fibrinogen, blood viscosity, blood plasma viscosity,red cell aggregation, the imitating thrombosis test of the length and weight of thrombus, the thrombus index Q are lower than these before treatment.Conclusion Defibrase is effective in treating patients with UAP by improving the hemorheological properties.
出处
《中国血液流变学杂志》
CAS
2004年第2期224-226,共3页
Chinese Journal of Hemorheology
