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在神经损伤疾病治疗中的用药分析

Analysis of rational administration in the treatment of nerve injury
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摘要 目的 探讨神经损伤患者治疗中出现的类似感染症状的药物治疗对策。方法 分析治疗过程中药物对疾病转归的影响。结果 神经损伤疾病患者在治疗过程中,出现发热及消化道症状,呈血清病样改变;胃肠道粘膜溃疡,肠道充血水肿,炎性细胞浸润,脓血便或粘液便等;有时合并肺片异常及浆膜腔炎等类似感染症状,一般使用抗菌药治疗,疗效不明显,但给予复方苯乙哌啶或同时联用免疫抑制剂治疗,有明显的疗效。结论 复方苯乙哌啶对神经损伤治疗过程中类似感染症有明显疗效。 Objective To discuss the reason of compound diphenoxylate or immunodepressant can relieve infection appearance of nerve injury patient. Methods The main factor of medication influence upon prognosis of disease during treatment was analyzed and investigated by drawing assistance from data of three nerve injury patients' cases together with literature reviewing. Results After analyzing and investigation, it was found that peptide hormone mediated inflammatory reaction of pathological changes process through immunology mechanism, which was released by organism nervous system that received tension and excitation of trauma. So peptide hormon antagon and immunodepressant are efficacious. It was inadvisable that promoting prolactin externalization drug-Cimetidine was used by nerve patient long-term. Conclusion Compound diphenoxylate had a clinical efficacy in treatment of infection of nerve injury.
作者 姜玲敏
机构地区 解放军
出处 《中国临床药理学杂志》 CAS CSCD 北大核心 2004年第3期209-211,共3页 The Chinese Journal of Clinical Pharmacology
关键词 神经损伤 免疫炎症反应 复方苯乙哌啶 nerve injury immunization inflammatory reaction compound diphenoxylate
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