摘要
目的 :提高对老年人单纯收缩期高血压 (isolatedsystolichypertensionintheelderly ,EISH)治疗的认识。方法 :EISH患者 88例 ,选用二氢吡啶类钙拮抗药 (dihydropyridinescalciumchannelblocker,CCB)和 (或 )小剂量利尿药 ,根据有否并发症和气温变化对血压的影响 ,进行选择性联合用药 ,实行个体化用药治疗 ,并根据昼夜血压变化规律服药。结果 :病人依从性和治疗率达 10 0 % ,总有效控制率达 90 %。患者治疗前后收缩压分别为 (2 2 8± 1 8)kPa、 (19 0± 1 9)kPa ,差异有统计学意义(P <0 0 1)。冬、春季加强降压和通血管治疗 ,无 1例发生脑卒中、急性心肌梗死和肾功能不全 ,长效CCB不良反应水肿仅占 13%。结论 :长效CCB和 (或 )小剂量利尿药降压 ,不良反应小 ,降压效果好 ,是治疗EISH的首选。密切医患关系 ,健康保健和疾病治疗相结合 ,配合健康生活方式 ,是提高治疗率和控制率的关键。
Objective:To enhance the awareness of treatment of isolated systolic hypertension in the elderly (EISH).Methods: The blood pressure was compared before and after treatment in 88 cases with EISH by combinations of dihydropyridines calcium channel blocker(CCB) and/or low dose diuretic on an individual basis according to complications, temperature and the circadian blood pressure. Results: Both the compliance and treatment rates reached 100%. The total effective rate on blood pressure control was 90% compared with pretreatment circadian(P<0.01).Before and after treatment the systolic blood pressure was (22.8±1.8)kPa and(19.0±1.9)kPa respectively(P<0.01). Not any stroke, acute myocardial infarction or renal function impairment was observed. Conclusions: The combination of long-acting CCB and/or low dose diuretic is the first choice for treatment of EISH because of few adverse effects and good efficacy.
出处
《新医学》
北大核心
2004年第7期404-405,共2页
Journal of New Medicine
关键词
老年人
单纯收缩期高血压
治疗
诊断标准
Elderly Isolated systolic hypertension Individualized therapy Dihydropyridines calcium channel blocker Diuretic
