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佛山市南海区534例0~5岁出生缺陷儿童临床分析

Clinic analysis on 534 children wth birth defects at the age of 0~5
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摘要 目的 分析南海区 0~ 5岁儿童出生缺陷发生率、种类、分布特征。方法 对南海区 5 34例 0~ 5岁出生缺陷儿童进行临床分析。结果  5年全区共发生出生缺陷儿童 5 34例 ,发生率为 9 1‰ ,男、女发生率分别为 10 2‰、7 8‰ ,男婴明显高于女婴。先天性心血管疾病发生率居首位 ,以 1999年至 2 0 0 0年发生出生缺陷的比例最高 ,发生率为 9 9‰。出生缺陷的发生在季节中的分布以秋、冬季发生率较高。在孕期中母亲有不同程度感染史和接触有害有毒物质 ,以及父母有特殊嗜好。结论 南海区出生缺陷发生率低于全国平均水平 ,与广东省的平均水平接近。男婴高于女婴、与怀孕季节有关 ,与孕妇年龄、文化程度、胎次无明显相关性。父母不良嗜好、孕期感冒、发热、接触化工材料、电脑等 ,可能是导致出生缺陷的危害因素。 Objective: To investigate the incidence, kind, and distribution features of children with birth defects at 0~5 years old in Nanhai district. Methods: Set up clinic analysis on 534 childrenwith birth defects at the age of 0~5 in Nanhai district. Results: Within five years, the occurrence of birth defects was 534 cases in this district, and the incidence 9.1‰, for male and female, respectively was 10.2‰ and 7.8‰. The former was significantly more than the latter. Among all birth defects, the incidence of congenital cardiovascular disease was the top one, and it was 9.9‰ during 1999~2000. In addition, the incidence of birth defects was also higher in autumn and winter. All mothers of children wth birth defects had the history of suffering different degrees of infection and touching harmful or poisonous matters, and some special hobbies. Conclusion: The incidence of birth defects in Nanhai district was lower than the average at the country, but close to the average of Guangdong province. That the incidence of male with birth defects was higher was related to pregnant season, not to pregnant age, education background and birth or times. Parent's bad hobbies, prenatal common cold, fever, touching chemical matters and computer may be dangerous factors for birth defects.
作者 黄丽贤
出处 《中国优生与遗传杂志》 2004年第3期92-93,98,共3页 Chinese Journal of Birth Health & Heredity
关键词 出生缺陷 发生率 相关因素 Birth defect Jncidence Relative factors
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