摘要
为了研究单复频超声激活血卟啉对人体肿瘤细胞的杀伤效应,利用自制的复频聚焦换能器激活血卟啉,以肿瘤细胞K562为研究对象,采用MTT法(四唑盐比色法)检测在不同超声处理时间、不同频率、不同溶液环境下、不同孵育时间条件下,声动力学激活血卟啉法对肿瘤细胞的杀伤效应。结果表明,复频聚焦超声激活血卟啉对肿瘤细胞具有较强的杀伤效应,是一种有应用前景的治疗肿瘤的新技术。
A bi-frequency focusing ultrasonic transducer is used to activate hematoporphyrin in order to kill cancer cells of K562. The cell-killing effects of the sonodynamic-therapy with different time, frequencies, liquor conditions and incubation time are studied. It is concluded that bi-frequency focused ultra-sound can increase the cell-killing effect in homodynamic therapy. The longer the irradiation time, the better the cell-killing effect.
出处
《声学技术》
EI
CSCD
2004年第2期84-87,共4页
Technical Acoustics
