摘要
目的 探讨胃癌根治术中腹腔留置力尔凡与5-氟脲嘧啶对患者术后生存期的影响。方法回顾性分析哈医大附属肿瘤医院2001年63例胃癌根治术后患者,其中术中腹腔留置力尔凡与5-氟脲嘧啶者27例,未留置者36例,对比其1年及2年生存率。结果Ⅱ期患者留置者1年及2年生存率分别为100％、83.3％,未留置者分别为87.5％、75％Ⅲ期患者留置者1年及2年生存率分别为80％、70％,未留置者分别为78.6％、57.1％;Ⅳ期患者留置者1年及2年生存率分别为81.8％、54.5％,未留置者分别为78.6％、.50％。虽然各期留置药物看与未留置药物者间1年及2年生存率经x2检验无显著性差异(P>0.05),但是各期留置药物者1年及2年生存率均较未留置者有提高趋势,尤其Ⅲ期2年生存率更为明显。结论 胃癌根治术中腹腔留置力尔凡与5-氟脲嘧啶是值得继续临床观察和完善的改善手术效果和延长患者生存时间的一种有益探索。
Objective To explore the survival time about administration and no administration of LIFEIN and 5 - FU into the peritoneal cavity during radical operation for stomach carcinoma. Methods To analyze retrospectively 63 cases performed radical gastrectomy, in them, LTFEIN vere given to 27 cases to compare their 1 - year and 2 - year survival rates. Results The 1 - year and 2 - year survival rates of stage Ⅱ of the group with LIFEIN and 5 - FU were 100% ,83.3% and another group without them were 87.5% ,75% respectively; The 1 - year and 2 - year survival rates of stage Ⅲ with LIFEIN and 5 - FU and without them were 80%,70%, theit of stage Ⅳ were 81.8%,54.5% and 78.6% ,50% respectively. Though there is no difference between them according to Chi-squre, the 1 - year and 2 - year survival rates of administration groups of each stage have higher trend than that of no administration, especially in stage Ⅲ . Conclusion During radical gastrectomy, administering LIFEIN and 5 - FU into the peritoneal cavity is a kind of good exploration which is worthy for clinical trial and reforming in order to improve the operation and prolong the patients survival time.
出处
《实用肿瘤学杂志》
CAS
2004年第3期173-174,共2页
Practical Oncology Journal
