摘要
目的探讨内镜下射频消融术治疗食管和胃的低级别上皮内瘤变的有效性及安全性。方法回顾性分析解放军总医院消化内镜中心2014年10月至2015年1月行内镜检查,经病理证实为食管或胃低级别上皮内瘤变的21例患者纳入研究,经门诊行内镜下射频消融治疗,其中食管部病变射频消融2次,胃部病变射频消融3次,术后采用Wang-Baker面部表情量表进行疼痛评分,治疗后1个月进行内镜复查。结果 21例共计31个低级别上皮内瘤变病灶纳入研究。16例共计23个低级别上皮内瘤变病灶进行了复查,其中14例患者,21个病灶经射频治疗后消失,病灶消除率91.30%(21/23);2例患者2个低级别上皮内瘤变病灶出现残留,病灶残留率8.70%(2/23)。16例复查患者病灶治疗部位黏膜均愈合,术后腹痛为主要并发症。结论内镜下射频消融术治疗食管和胃低级别上皮内瘤变是安全、有效、并发症小、可门诊治疗的一种新方法。
Objective To evaluate the efficacy and safety of radiofrequency ablation ( RFA) for esophageal and gastric low-grade intraepithelial neoplasia ( LIN) .Methods We retrospectively enrolled 21 patients with LIN of esophagus and stomach who were treated with RFA under endoscopic at the General Hospital of PLA from October 2014 to January 2015 .Two pulses were used to ablate the esophageal lesions and three pulses were used to ablate the gastric lesions .Pain scores were recorded using Wang-Baker facial pain scale.A month later, patients underwent regular endoscopy follow-ups.Results A total of 31 LIN lesions of 21 patients were included in the study .Twenty-three lesions of 16 patients underwent endoscopy follow-ups after 1 month.The lesions elimination rate was 91.30%(21/23)and the lesions residual rate was 8.70%(2/23).The RFA treatment lesions of 16 patients healed by endoscopy follow-up and postoperative pain was the main complications .Conclusion RFA is considered to be safe and effective , which can be performed in the outpatient service .
出处
《中华胃肠内镜电子杂志》
2015年第1期14-17,共4页
Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)
基金
北京市科技计划课题(D141000000414003)
关键词
内窥镜检查
低级别上皮内瘤变
射频消融术
食管
胃
Endoscopy
Low-grade intraepithelial neoplasia
Radiofrequency ablation
Esophagus
Stomach
