摘要
目的:探讨社区门诊使用缬沙坦联合硝苯地平治疗老年性高血压的临床疗效。方法:选取我社区门诊在2011年1月至2013年10月收治的高血压患者120例,将其随机分为A组、B组和C组三组,A组单独给予缬沙坦治疗,B组单独给予硝苯地平缓释片治疗,C组联合应用缬沙坦和硝苯地平缓释片治疗,比较三组的治疗效果。结果:治疗2个月后,三组患者的DBP、SBP均明显下降(P<0.05),且与A、B两组相比,C组患者下降更为显著(P<0.05);三组疗效比较,C组治疗总有效率(92.5%)明显大于A组(77.5%)和B组(75.0%),且P<0.05;三组患者治疗期间均未见明显不良反应。结论:联合应用缬沙坦和硝苯地平治疗老年高血压患者的疗效显著,值得在临床上推广。
Objective: To investigate the clinical efficacy of valsartan and nifedipine community outpatient treatment of patients with senile hypertension.Methods: the community clinics in 120 hypertensive patients from 2011 January to 2013 October in our hospital, were randomly divided into A group,B group and C group three, A group was received valsartan in the treatmentgroup, B alone Extended Release Nifedipine Tablets treatment, C group of valsartan and nifedipine sustainedrelease tablets in the treatment, and compare the three the treatment effect. Results: after 2 months of treatment,three groups of patients with DBP, SBP decreased significantly(P<0.05), andcompared with A, B two groups, patients in group C decreased significantly(P<0.05); to compare the effects of three groups, C treatment group total effective rate(92.5%) was significantly higher than that in A group(77.5%)and group B(75%), and P<0.05; during the treatment of the three groupswere no obvious adverse reactions. Conclusion: the combination of valsartan and nifedipine in the treatment of senile hypertension patientssignificantly,worthy of clinical application.
关键词
老年
高血压
缬沙坦
硝苯地平
疗效
The elderly
Hypertension
Stan
Nifedipine
Curative effect
