摘要
目的 :探讨检测上尿路结石患者肾小球滤过率的临床意义。方法 :对2009年1月~2013年12月期间我院收治60例上尿路结石患者(共有71个患肾)的临床资料进行回顾性研究。我们使用99mTc-DTPA肾动态显像检测法对这60例患者71个患肾的肾小球滤过率(GFR)进行检测。结果 :我们对这71个患肾的肾小球滤过率进行检测和分析后发现,它们中有67个患肾存在上尿路完全梗阻或不完全梗阻的情况。后经手术勘察证实,这71个患肾全部存在上尿路完全梗阻或不完全梗阻的情况。用检测肾小球滤过率的方法诊断上尿路结石引起的上尿路完全梗阻或不完全梗阻的准确率为94.4%。同时,我们根据67例进行肾小球滤过率检测被确诊发生上尿路完全梗阻或不完全梗阻患者肾小球滤过率的检测结果,将他们分为肾功能正常组(有20人)、肾功能轻度损伤组(有18人)、肾功能中度损伤组(有18人)和肾功能重度损伤组(有11人)。在这67例患肾上尿路梗阻解除前,这四组患者肾小球的滤过率分别为43.93±2.6 mL/min、23.45±1.3mL/min、16.22±3.7 mL/min和7.92±3.4 mL/min。在这60例患者上尿路梗阻解除3个月后,他们肾小球的滤过率分别为48.72±1.7 mL/min、42.22±3.6 mL/min、33.13±4.1 mL/min和17.88±3.8 mL/min。这一结果说明,上尿路梗阻解除前肾功能较差的上尿路结石患者,其肾功能在上尿路梗阻解除后恢复的情况较差。结论 :检测上尿路结石患者的肾小球滤过率可有效发现其存在的上尿路梗阻,同时可以对其解除梗阻后肾功能的恢复情况进行准确的预测。此检测方法值得在临床上推广使用。
Objective: To investigate the clinical significance of urinary stone patients with glomerular filtration rate. Methods: from 2009 to January to 2013 December in our hospital during the period 60 cases of upper urinary tract calculi(a total of 71 patients with renal) retrospective study. We use the 99mTc-DTPA renal dynamic imaging detection method of these 60 patients, 71 patients with renal glomerular filtration rate(GFR) detection. Results: the 71 patients with renal glomerular filtration rate detection and analysis found that, there are 67 patients of upper urinary tract obstruction of renal exist or incomplete obstruction situation they are in. After investigation confirmed that the 71 operation, kidney all complete obstruction of upper urinary tract or incomplete obstruction of. The accurate rate of complete obstruction caused by diagnostic tests for glomerular filtration rate of upper urinary tract calculi of upper urinary tract or incomplete obstruction was 94.4%. At the same time, we according to the 67 cases of glomerular filtration rate of upper urinary tract obstruction is complete or incomplete obstruction in patients with glomerular filtration rate detection results confirmed, divided them into normal renal function group(20 people), renal function in mild injury group(18 people), renal function injury group(the degree 18) and renal function in severe injury group(11 people). Of the 67 patients with upper urinary tract obstruction was lifted, the four groups of patients with glomerular filtration rate were 43.93 ± 2.6 mL/min, 23.45 ± 1.3 mL/min, 16.22 ± 3.7 mL/min and 7.92 ± 3.4 mL/min. In the 60 cases of patients with upper urinary tract obstruction after 3 months, their glomerular filtration rate were 48.72 ± 1.7 mL/min, 42.22 ± 3.6 mL/min, 33.13 ± 4.1 mL/min and 17.88 ± 3.8 mL/min. This result suggests that, in patients with upper urinary calculi of upper urinary tract obstruction of poor renal function, the renal function recovered in the upper urinary tract obstruction after the lifting o
