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Novel Elastomeric Fabrics for the Treatment of Hypertrophic Burn Scars Using Polyhexamethylene Biguanide Antimicrobial Agents

Novel Elastomeric Fabrics for the Treatment of Hypertrophic Burn Scars Using Polyhexamethylene Biguanide Antimicrobial Agents
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摘要 In burn treatments,microorganisms on pressure garments during pressure therapy can prevent rehabilitation by causing functional,hygienic,and aesthetic difficulties. As bacterium is one of the most trouble-causing organisms,they can threaten patients causing infection during the long period of use of these garments.Novel burn pressure garments having durable antimicrobial property were developed using polyhexamethylene biguanide( PHMB)antimicrobial agent procedure on highly elastic nylon 66 /spandex fabrics in powernet,flat warp and weft knitted structures using paddry-cure method. Commercial wireless pressure sensors were used to control pressures at an acceptable medical range. Antimicrobial activity,wash durability,Fourier transform infrared spectroscopy(FTIR) and Scanning electron microscopy(SEM) analyses were conducted for the treated samples. Antimicrobial test results following AATCC 100 Test Method showed 99% reduction of bacteria for the fabric samples treated with PHMB. A small but significant decrease in antimicrobial activity was observed even after50 launderings. These treatments also yield good results to prevent odor,decrease infection by preventing and /or blocking microbial growth according to the antimicrobial mechanism and support reducing of scarring by providing a hygienic environment around the scar. In burn treatments,microorganisms on pressure garments during pressure therapy can prevent rehabilitation by causing functional,hygienic,and aesthetic difficulties. As bacterium is one of the most trouble-causing organisms,they can threaten patients causing infection during the long period of use of these garments.Novel burn pressure garments having durable antimicrobial property were developed using polyhexamethylene biguanide( PHMB)antimicrobial agent procedure on highly elastic nylon 66 /spandex fabrics in powernet,flat warp and weft knitted structures using paddry-cure method. Commercial wireless pressure sensors were used to control pressures at an acceptable medical range. Antimicrobial activity,wash durability,Fourier transform infrared spectroscopy(FTIR) and Scanning electron microscopy(SEM) analyses were conducted for the treated samples. Antimicrobial test results following AATCC 100 Test Method showed 99% reduction of bacteria for the fabric samples treated with PHMB. A small but significant decrease in antimicrobial activity was observed even after50 launderings. These treatments also yield good results to prevent odor,decrease infection by preventing and /or blocking microbial growth according to the antimicrobial mechanism and support reducing of scarring by providing a hygienic environment around the scar.
出处 《Journal of Donghua University(English Edition)》 EI CAS 2013年第5期410-415,共6页 东华大学学报(英文版)
基金 Financial support of this research was provided by NC State University College of Textiles the Scientific and Technological Research Council of Turkey
关键词 PRESSURE GARMENTS BURN HYPERTROPHIC SCARS antimicrobial polyhexamethylene biguanide(PHMB) wireless PRESSURE sensors pressure garments burn hypertrophic scars antimicrobial polyhexamethylene biguanide(PHMB) wireless pressure sensors
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参考文献3

  • 1Dafu Wei,Qiangxiang Ma,Yong Guan,Fuzeng Hu,Anna Zheng,Xi Zhang,Zheng Teng,Hua Jiang.Structural characterization and antibacterial activity of oligoguanidine (polyhexamethylene guanidine hydrochloride)[J].Materials Science & Engineering C.2009(6) 被引量:1
  • 2Nilüfer Y?ld?z.A novel technique to determine pressure in pressure garments for hypertrophic burn scars and comfort properties[J].Burns.2006(1) 被引量:1
  • 3Lisa Macintyre,Margot Baird,Phil Weedall.The study of pressure delivery for hypertrophic scar treatment[J].International Journal of Clothing Science and Technology.2004(1) 被引量:1

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