摘要
本文总结了我院应用吗苯咯酮于各种全麻后催醒及治疗药物中毒病人共61例。其临床效果及额肌电(EMGf)/电脑处理的数量化脑电图(EEGcq)的特征性变化表明:该药对安定、哌替啶、芬太尼、羟基丁酸钠、硫喷妥钠、N2O-异氟醚、普鲁卡因等全麻药具有快速、确切的催醒作用,有效率达96％;且显著兴奋呼吸、改善血气检测值。14例心功较差的二尖瓣替换术病人于体外转流后应用吗苯咯酮证实,在1～2 mg·kg-1用量内,对血流动力学影响轻微。
We used doxapram hydroehloride (DH) as an analeptic after Various anesthesia and acute drug poisoning in 61 patients. The characteristic changes of computerized quantit-ative electroencephalogram (EEGcq) and frontal electromyogram (EMGf) and clincal effectiveness showed that DH had rapid and reliable analeptic effect on diazepam,pethidine, fentany1, γ-OH, thiopental or nitrous oxide-isoflurane anesthesia, stimulated breath powerfully and improved blood gas values. The application after CPB in 14 patients undergoing mitral valvular replacement confirmed that the effects of DH on the hemody-namics were slight.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1989年第1期3-7,共5页
Journal of Clinical Anesthesiology
