摘要
目的探讨四联疗法(含左氧氟沙星)较三联疗法在根治幽门螺杆菌(Hp)感染方面的优越性,为将来治疗与Hp相关疾病制定合理的治疗方案奠定基础。方法将内科门诊经确诊后治疗的Hp阳性慢性胃炎患者给予四联疗法(观察组)与三联疗法(对照组)治疗,观察2组在根治Hp方面的效果及临床疗效。结果观察组Hp的根治率为81.5%,而三联疗法的根治率为71%;在临床复发方面,观察组复发率为18.5%,而对照组复发率为29%;差异有统计学意义(P<0.05)。结论四联疗法是目前根治Hp相关性胃炎的首选疗法,值得临床推广应用。
Objective To investigate the quadruple therapy(including levofloxacin) a triple therapy in eradicating helicobacterpylori(Hp)infection,theadvantageoftotreatdiseasesassociatedwithHpforthefuturetoestablishareasonable foundation treatment. Methods Will internal medicine outpatient treatment after diagnosis of Hp+ to quadruple therapy of chronicgastritispatients(observationgroup)andtripletherapy(controlgroup)treatment,observetheeffectofthetwogroupsin termsoferadicatingHp+andclinicaleffect.Results ObservationgroupineradicatingHpis81.5%,thecurerateforthetriple therapy in the cure rate of 71%. In the aspect of clinical relapses, observation group recurrence rate 18.5%, and control the recurrencerateis29%;P<0.05,thedifferencewasstatisticallysignificant.Conclusion Quadrupletherapyisthetreatmentof choiceforradical+Hpcorrelationgastritis,worthyofclinicalpopularizationandapplication.
出处
《基层医学论坛》
2013年第S1期8-10,共3页
The Medical Forum
关键词
胃炎
HP
三联疗法
四联疗法
根治
Gastritis Hp Tripletherapy Quadrupletherapy Cure
