摘要
目的总结腹腔镜胆囊切除术中(laparoscopic cholecystectomy,LC)意外胆囊癌(unsuspected gallbladder carcinoma,UGC)的治疗经验,探讨其应对策略。方法回顾性分析我院8000例LC术中及术后诊断为UGC的16例临床资料。结果所有16例胆囊癌病例中,在LC术中诊断7例,LC术后诊断有9例,其中NevinⅠ期2例、Ⅱ期6例、Ⅲ期7例、Ⅳ期1例。患者的5年存活率NevinⅠ期为100%,Ⅱ期的5年存活率为66.7%,Ⅲ期和Ⅳ期未有5年存活者。结论 UGC患者的存活与肿瘤分期相关,NevinⅠ期胆囊癌,行LC即可。LC术中怀疑有胆囊癌应及时行冰冻病理检查,对于确诊NevinⅠ期以外的UGC应该尽早开腹行胆囊癌根治术。
Objective To generalize the treatment experience of 16 patients with unsuspected gallbladder carcinoma(UGC)during or after laparoscopic cholecystectomy(LC),review the literatures,and investigate its management strategies.Methods Clinical data of the patients with UGC during or after LC were reviewed retrospectively.Treatment strategies and prognosis were analyzed.Results Among 8000 LC cases in our hospital,there were 16(0.2%) UGC cases including 7 diagnosed during LC operation and 9 confirmed postoperatively.There were 2 cases with Nevin Ⅰ stage,6 with Nevin Ⅱ,7 with Nevin Ⅲ and one with Nevin Ⅳ stage.The five-year survival rates of NevinⅠand Ⅱ staged patients were 100% and 66.7% respectively,while there was no 5-year survivors in Nevin Ⅲ and Ⅳ staged patients.Conclusions The survival rate of UGC is associated with tumor stage.If UGC is suspected,intraoperative frozen section should be performed for pathological confirmation.LC operation is adequate for Nevin Ⅰ staged cancer and radical operations are recommended for the patients with stage more than Nevin Ⅰ.
出处
《消化肿瘤杂志（电子版）》
2010年第2期108-111,共4页
Journal of Digestive Oncology(Electronic Version)
关键词
腹腔镜胆囊切除术
胆囊癌
意外胆囊癌
Laparoscopic cholecystectomy
Gallbladder carcinoma
Unsuspected gallbladder carcinoma
