摘要
目的探讨罗哌卡因复合地佐辛进行臂丛神经阻滞麻醉行上肢手术的麻醉效果。方法随机抽取于2011年1月~2013年9月在南阳市中心医院麻醉科接受上肢手术治疗的患者180例,平均分成A、B、C共3组。A组患者注射0.4%罗哌卡因25 mL进行麻醉操作;B组首先进行与A组同样的麻醉操作,然后再通过静脉注射地佐辛10 mg辅助麻醉;C组注射0.4%罗哌卡因与10 mg的地佐辛混合液共25 mL。比较3组患者麻醉效果与不良反应。结果 C组患者的麻醉起效时间最短,为(17.43±1.53)min,3组间比较差异无统计学意义;C组感觉阻滞持续时间与镇痛持续时间分别为(8.22±1.63)h和(11.33±1.90)h,均比A组和B组长,且组间比较差异具有统计学意义(P<0.05);C组在手术开始各时间点目测类比评分法(visual analogue scale,VAS)评分较A组和B组低,但3组间比较差异无统计学意义。C组手术后1 h、6 h、12 h以及24 h VAS得分均低于A组和B组,且组间比较差异显著(P<0.01)。结论对臂丛神经阻滞的患者复合使用罗哌卡因与地佐辛,可显著增强麻醉效果,延长镇痛持续时间。
Objective To research the anesthetic effect of ropivacaine compounding with dezocine on brachial plexus block.Methods From January 2011 to September 2013,180 cases upper extremity surgery patients were selected and divided into group A,group B and group C in Nanyang Central Hospital.Patients in group A received 25 mL 0.4%ropivacaine injection for brachial plexus block;based on group A,group B was injected 10 mg dezocine to assist anesthesia;group C received a mixture of 25 mL 0.4% ropivacaine and 10mg dezocine injection.The anesthetic effect and adverse reactions of the patients in three groups were recorded and compared. Results The onset of anesthesia of group C was(17.43 ±1.53)min,which was the shortest of three groups,but there were no significant differences.The duration of sensory blockade and duration of analgesia was(8.22 ±1.63)h and (11.33 ±1.90)h,which were all longer than group A and group B,and there was significant differences(P<0.05);the visual analogue scale(VAS) scores of group C at each time before surgery was the shortest,but there were no significant differences.The VAS scores of group C at 1 h,6 h,12 h and 24 h after surgery were all lower than group A and B,and there were no significant differences.Conclusion Ropivacaine compounding with dezocine on brachial plexus block can improve the effect of anesthesia,extend the duration of analgesia.
出处
《中国生化药物杂志》
CAS
北大核心
2014年第4期105-107,110,共3页
Chinese Journal of Biochemical Pharmaceutics
基金
浙江省医药卫生一般研究计划(2012KYB046)
