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新生儿疾病与C反应蛋白和纤维连结蛋白的关系

THE RELATIONS BETWEEN NEONATAL DISEASE AND THE VALUE OF CRP AND FN
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摘要 本文报告50例新生儿患者在其疾病的不同时期血中C反应蛋白[CRP]和纤维连结蛋白[Fn]测定结果,新生儿感染性疾病40例,非感染性疾病10例,测定显示在新生儿感染性疾病的早期CRP即高于正常,Fn低于正常;于感染的极期,CRP水平显著增高,Fn明显降低;随着感染的控制;CRP趋于恢复,Fn也逐渐回升,认为CRP和Fn的联合测定及动态观察可作为新生儿感染早期诊断和疗效估计的重要指标之一。 Serum C reactive protein and Fibronectin level were examined in 50 newborn patients in different periods of neonatal diseases. These included 40 septic neonates and 10 noninfectious cases. It was showed that CRP level was higher than normal while Fn level was lower than normal in early days of infection. As the infection got severer, these changs became more noticeable. Alone with the infection being well-controlled, the value of CRP decreased and Fn level returned to normal. The authors consider that dynamic observation of serum CRP and Fn can be used as one of the chief indexes of early diagnosis and evaluation of curative effect in neonatal infectious diseases.
机构地区 四川省人民医院
出处 《中国新生儿科杂志》 CAS 1991年第2期65-66,92,共3页 Chinese Journal of Neonatology
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