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Growth Disorder in NRK Cells Caused by Overexpression of Protein Kinase Cβ I Subtype

Growth Disorder in NRK Cells Caused by Overexpression of Protein Kinase Cβ I Subtype
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摘要 Protein kinase C(PKC) is a multifunctional protein kinase which belongs to amultigene family of fundamental importance in growth regulation of the cells. Manystudies have indicated that the distinct isoenzymes exhibit different cell functions.To further elucidate the functional role of specific forms of PKC in growth controland their possible molecular mechanisms, we have constructed the NRK cell modelthat overexpressed PKCβ I isoform for the first time. Furthermore, we have
机构地区 Department of Biology
出处 《Chinese Science Bulletin》 SCIE EI CAS 1994年第7期592-596,共5页
基金 Project supported by the National Natural Science Foundation of China.
关键词 protein kinase I (PKCβ I) GROWTH oncogene. protein kinase Cβ I (PKCβ I), growth, oncogene.
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