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肿瘤坏死因子(TNF)的分子结构和生物学活性 被引量:1

MOLECULAR STRUCTURE AND BIOLOGICAL ACTIVITY OF THE TUMOR NECROSIS FACTOR (TNF)
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摘要 TNF最初被发现是因为它显示了抗癌活性,现已判定它是免疫细胞接受某些特定的刺激因子所产生的多功能细胞因子,它参与了炎症和免疫反应以及细胞生长或抑制的各种蛋白质因子中的一族,本文讨论了TNF的分子结构和生物学活性及两者之间的关系。 TNF were initial discovered just because they showed anticarcinogenic activity. Now they have been identified as multi-function cytokine produced by immunocytes which are stimulated by specific factor. In addition, TNF partipate in inflammatory and immune re-sponses, and consist of one family of variety of protein factor, relate to cell growth or sup-pression. This paper discusses TNF's molecular structure and their biological activities and relations between both.
出处 《新疆师范大学学报(自然科学版)》 1994年第2期74-78,92,共6页 Journal of Xinjiang Normal University(Natural Sciences Edition)
关键词 TNF LPS 恶性肿瘤 炎症和免疫反应 LPS Inflammatory and immune responses Maligmancy.
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