摘要
为了解作者培育的近交系ＮＪＳ小鼠的生化、免疫、形态等遗传学性状，对该小鼠的生化标志基因、免疫标志基因、毛色基因进行测试，并作下颌骨形态分析。结果表明：ＮＪＳ小鼠是一株新培育的近交品系，具有独特的遗传特性。所检的分布在１２条染色体上的２６个生化标志基因未见与其它近交系小鼠完全相同。Ｈ－２位点基因为Ｈ－２Ｋｄ、Ｈ－２Ｄｋ。毛色基因型为ＡＡＢＢｃｃＤＤ。下颌骨形态判别函数ＤＦ１、ＤＦ２、ＤＦ３、ＤＦ４值分别为４．５１、－６．３１、０．１６、－０．８５。与近交系ＢＡＬＢ／ｃ、Ｃ５７ＢＬ／６、６１５、ＳＭＭＣ／ｃ的遗传距离分别为８３．１９、６２．８７、４１．３４、２２．４４。
In order to underseand the biochemical,immune and shape traits in inbred NJS strain mouse,the biochemical marker,histocompatibility-2 complex,coat color were researched and the mandible shape was analysed.The results showed NJS mouse was a newbred inbred strain with particular genetic characteristics.Its twenty-six biochemical marker genes distributed over tweleve chromosomes are not all dentical to other inbred strains,Its H-2 genes are H-2Kd,H-2Dk.genotype of coat color is AABBccDD,Its differential function DF1～DF4 of the mandible shape is 4.51,6.31,0.16,0.85 respectively.The genetics distance to BALB/c,C57BL/6,615,SMMC/c is 83;19,62.87,41.34,22.44 respectively。
出处
《医学研究生学报》
CAS
1996年第3期227-230,共4页
Journal of Medical Postgraduates
基金
南京军区"八五"招标中青年课题
