摘要
目的 探讨慢性阻塞性肺病急性感染期致病菌变化及其耐药性,为合理应用抗生素提供可靠依据。方法 对46例慢性阻塞性肺病急性感染期患者与30例急性下呼吸道感染进行痰菌培养及药物敏感的对照分析。结果 慢性阻塞性肺病急性感染期多为混合菌感染,革兰氏阳性球菌感染减少,革兰氏阴性杆菌、真菌、厌氧菌增多,且耐药性严重,与对照组比较有显著意义。结论 监测慢性阻塞性肺病急性感染期致病菌变化及其耐药性,可指导临床选择抗生素,预测病情进展。
Objective To provide reliable proof for using antibiotic by studying pathogen change and antibiotic resistance in patients with acute infection period of chronic obstructive pneumonia disease (COPD). Methods Analyze the phlegm bacterial culture and antibiotic sensitivity in 46 COPD patients with acute infection period compare to 30 patients with lower respiratory tract acute infection. Results In COPD patients,most were polyinfection,gram-positive coccus bacteria were significantly decreased,gram-negative bacillus bacteria,eumycetes,anaerobes were increased had serious antibiotic resistance significance had shown for COPD patients than controls. Conclusion Monitoring pathogen change and resistance in COPD patients with acute infection period,can instruct we choose antibiotic,anticipate the program of disease.
出处
《青岛医药卫生》
1999年第1期60-61,共2页
Qingdao Medical Journal
关键词
慢性阻塞性肺病
痰培养
药敏
Chronic obstructive pneumonia disease Phlegm bacterial culture Antibiotic sensitivity
