摘要
目的对环孢素和他克莫司治疗术后肾移植患者进成本效用分析。方法应用WHOQOL-BREF对2007年11月～2008年6月期间到南方医院就诊的186名肾移植门诊患者的生存质量进行评价,然后利用生存质量的得分,结合患者药物费用进行成本/效用分析。结果环孢素组在心理、社会关系及量表总得分高于他克莫司组,差异显著(Ρ<0.05);而在生理和环境领域方面两组差别不显著(P>0.05)。在药品费用成本方面,环孢素组比他克莫司低,环孢素组患者每月平均费用为2 211.00元,而他克莫司组的为4 187.47元。结论服用环孢素的患者在心理和社会关系方面比服用他克莫司的患者好;环孢素、他克莫司对肾移植患者的生理和环境领域方面的影响无差异。成本效用分析显示,服用环孢素更经济实惠。
Objectives To compare the cost utility of cyclosporine and tacrolimus in kidney transplantation patients.Methods The quality of life of 186 kidney transplantation patients,among which 62 receiving cyclosporine treatment and 115 receiving tacrolimus treatment during Dec,2007 to June,2008 were evaluated by the WHOQOL-BREF.Then the score of the whoqol-bref and the drug cost were combined to analyze cost and utility.Results The patients of cyclosporine group gained more score in mental health,social relationship and total score with significant difference(Ρ<0.05).There was no significant difference in physiological and environment field(P>0.05).The every month's cost of the cyclosporine was 2211.00 yuan,and the tacrolimus's was 4187.47 yuan.Conclusions The patients with cyclosporine treatment was good than the patients with tacrolimus treatment in mental and social relationship field.There was no significant difference in physiological and environment field.The cost utility analysis showed that took cyclosporine is cost effective.
出处
《中国社会医学杂志》
2010年第5期313-314,317,共3页
Chinese Journal of Social Medicine
基金
国家自然科学基金项目(30471481)
广东省科技计划项目(2009B080701073)
关键词
环孢素
他克莫司
肾移植
生存质量
成本效用分析
Cyclosporine
Tacrolimus
Kidney transplantation
Quality of life
Cost-utility analysis
