摘要
本文对我院3年收治的96例血液系统肿瘤患者感染情况作一初步调查,观察到192例次住院中,发生感染169例次。发生率88.0%;感染与疾病严重度和白细胞减少有关,当 WBC≤2.0×10~9/L 感染发生率高达51.5%。感染部位以呼吸道最多见。霉菌感染不少见,检出率达25.9～54.0%,细菌与霉菌的双重感染发生率达38.3%。另外,在防治感染上我们体会到:口腔持续滴入灭滴灵和庆大霉素治疗口腔溃疡有疗效;对有肛门疼痛或坠胀感的白血病患者尽早行超短波治疗以防止肛周感染发展。绿脓杆菌 MSHA 菌毛株菌苗对化疗期间白血病患者具有一定抗感染和免疫调节作用,可作为一种有效的辅助治疗。
The infection in 96 in-patients of hematologic tumor in our hospital in a period of three years were investigated.There were 169 cases comp- licated with infections in 192 cases of in-patient.The rate of infection was 88.0%.Infection related to the severe state of the disease and the reduction of WBC.When WBC was less than 2.0×10~9/L,the rate of infection was up to 51.5%.Respiratory tract infection was the commenest. Infection by fungus was not rare.The positive finding of fungus was 25.9～54.0%.In addition,the oral ulcer treated by local dropping of metronidazole and gentamycin was effective.In order to prevent the spread of infection around anus,the ultrashort wave was used as early as possible to leukemia patients who had pain or heavy sensation in anus region.MSHA vaccine having immuno-regulated and antiinfection action is of value to leukemia patients during chemotherapy,as an auxiliary treatment.
