摘要
目的 观察丝虫病在当地的流行趋势,探讨临沂市消灭丝虫病成因。方法 对人群进行病原学监测及血清学监测(采用I-FAT):设立观测点对传播媒介的构成比、传播强度与作用进行定点监测;调查动物丝虫与人类的关系。对检出的微丝蚴阳性者给予4.2g海群生全程治疗,1年后再给以全程治疗。结果1984-2002年全市共血栓人群286 633人,达流行区总人口的5.73％,覆盖了全部流行乡镇的49.22％,微丝蚴总阳性率为0.023％,并呈逐年下降趋势;基本消灭丝虫病后出生的人群未发现阳性者;1987年后累计血检166 503人.占流行区总人口的3.33％,未发现微丝蚴阳性者。IFAT检测,丝虫特异抗体IgG4水平,基本消灭丝虫病前、后出生的人群差异有统计学意义。淡色库蚊为当地优势蚊种(50.75％),是当地人体斑氏丝虫病的唯一传播媒介;淡色库蚊幼丝虫感染率为0.029％,并逐年下降,至1988年已降为零;在捕到的阳性蚊蝶中,仅发现1只体内存有Ⅲ期幼虫;低密度微丝蚴血症者与人蚊接触机会的减少.使得蚊媒传播能力降低,进而切断了传播途径。动物丝虫阳性物种对人类及其传播媒介的作用,不能在人群中形成传播。结论监测结果证实,丝虫病在3地的传播已被阻断,该市达到了消灭丝虫病标准。
Objective To Observe the popular trend and approach the contributing factors on the eradication of filariasis in Linyi City. Methods The populations were surveied on etiology, IFAT anti - body level, transmitting vectors and the relationship between the animal filaria and human. Hetrazam(4.2g) was used to treat the persons carrying microfilaria, and treat them once again with the same method after a year. Results From 1984 to 2002, 286633 cases were sanguitested, which were 5.73% of the populations in the epidemical area of filariasis, the total positive rate of microfilaria was 0.023% and it was dropped year by year. The positive cases of microfilaria were not found in the populations bom after basic eradication of filariasis. 16650 cases were sanguitested after 1987,which were 3.33% of the populations in the epidemical area,the positive cases of microfilaria were not found. There was significant difference in antibody( IgG4) level of filaria tested by IFAT between the populations born before and after basic eradication of filariasis. Culex Pipiens Pallens was superior kind of mosquito( 50.75%) in this area, which was only a transmitting vector of humanity Bancroftion filariasis, the infections(by larva filaria) rate of which was 0. 029% , dropped year after year, and reached 0 in 1988. In all catched mosquito vectors, larva filaria Ⅲ were found only in one of them. As the chance that low density microfilaremia cases contacted with mosquito was reduced, the transmitting ability of mosquito vector was lower,so that the transmitting route of filariasis was cut off. The positive kind of animal infected filaria could not transmit to human and their transmitting vectors. Conclusion The results of surveillance showed that the transmitting route of flariasis was broken in the local place. The standards of the eradication of filariasis were achieved in the city.
出处
《中国煤炭工业医学杂志》
2004年第9期894-896,共3页
Chinese Journal of Coal Industry Medicine
关键词
丝虫病
监测
控制
微丝蚴
传播媒介
filariasis
surveillance
control
microfilaria
transmitting vector
