摘要
目的探讨现阶段乙肝病毒宫内感染的状况与新生儿乙肝标志物的阳性率及其临床应用。方法检测898例乙肝病毒携带者产妇及其新生儿乙肝标志物,并对新生儿HBcAb阳性者进一步作HBcAb-lgM检测。结果所有新生儿均未检测到HBsAg和HBeAg阳性;HBeAb和HBcAb结果与母亲结果高度相关;所有新生儿HBcAb-lgM全部阴性。结论阻断方法的应用使得宫内感染的情况已极少发生,新生儿HBeAb和HBcAb阳性不能作为感染过乙肝病毒的标志。
To investigate intrauterine infection of hepatitis B virus(HBV) and its relationship with positive rate of HBV markers of newborn infants,HBV makers of 898 HBV carriers of puerperants and their newborn infants had been analyzed.For HBcAb positive infants,a further detection of HBcAb-IgM was performed.The study showed that all newborn infants demonstrated HBsAg-and HBeAg-negative.Furthermore,the detection results of HBsAg and HBeAg were closely correlated with the results of the mothers’;all infants showed HBcAb-IgM negative.From above we presumed that HBV intrauterine infection could be prevented significantly by the use of interception method.And the positive results of HBeAb and HBcAb can not be regarded as the HBV-infected markers in newborn infants.
出处
《免疫学杂志》
CAS
CSCD
北大核心
2013年第2期180-181,共2页
Immunological Journal
关键词
产妇
新生儿
乙肝标志物
Puerperant
Newborn infant
HBV-marker
