摘要
目的探讨同步放化疗治疗晚期食管癌的临床疗效。方法选取收治的80例晚期食管癌患者作为研究对象。按照治疗方法的不同,分为化放组和单放组。通过近期客观疗效、生活质量、随访,综合评价同步放化疗及单纯放疗用于治疗晚期食管癌的临床疗效。结果化放组患者的近期有效率明显高于单放组,治疗后随访1年生存率明显高于单放组,其差异有统计学意义(P<0.05);但同时两组患者治疗后生活质量无明显差异(P>0.05)。结论同步放化疗较单纯放疗用于治疗食管癌的近期疗效有优势,但应注意化疗药物不良反应,提高患者生活质量。
Objective Explore the clinical efficacy of concurrent chemoradiotherapy for the treatment of advanced esophageal cancer.Method Select treated 80 patients with advanced esophageal cancer patients as research subjects.In accordance with the different treatment methods and is divided into the radiotherapy group and the radiotherapy alone group.By recent objective efficacy,quality of life,followup evaluation of concurrent chemoradiotherapy and radiotherapy alone for clinical efficacy in the treatment of advanced esophageal cancer.Results Recent of put patients was significantly higher than the radiotherapy alone group after treatment were followed up for 1-year survival rate was significantly higher than the radiotherapy alone group,the difference was statistically significant(P<0.05);but at the same time two groups of patients quality of lifeno significant difference.Conclusions Concurrent chemoradiation than a simple short-term effect of radiotherapy used for treatment of esophageal cancer have an advantage,but pay attention to the adverse effects of chemotherapy drugs improve patients' quality of life.
出处
《现代诊断与治疗》
CAS
2012年第12期2067-2068,共2页
Modern Diagnosis and Treatment
关键词
食管癌
同步放化疗
单纯放疗
近期疗效
esophageal cancer
synchronous radiotherapy and chemotherapy
radiotherapy alone
term efficacy
