摘要
目的了解云南保山市汉族7岁以下儿童地中海贫血和G6PD缺乏症的现状.方法对保山市两县1 358名7岁以下儿童采静脉血进行血细胞分析,用pH8.6缓冲液醋酸纤维薄膜做血红蛋白电泳分析;采用改良葡萄糖6-磷酸脱氢酶(G6PD)测定比值法(手工操作法)进行G6PD缺乏症检测.结果保山市汉族7岁以下儿童β-地中海贫血检出率为5.2%,α-地中海贫血检出率为4.6%,G6PD缺乏症检出率为0.7%,地中海贫血患病率男女童分别是9.3%和10.5%,无明显年龄和性别差异.结论云南保山地区汉族儿童地中海贫血高发,但G6PD缺乏症患病率较低.地中海贫血患病率无明显年龄和性别差异.
Objective To understand the prevenlance rates of thalassemia and G6PD deficiency among Han children under 7 years old in Baoshan,Yunnan.Metbod The total of 1,358 blood samples of children were tested by blood cell automatic analysis,hemoglobin electroph,and erythrocyte glucose-6-Phosphate dehydrogenase deficiency(G6PD)diagnostic kit.Results The prevenlance rates of β-thalassaemia,α-thalassaemia,and G6PD deficiency were 5.2%,4.6% and 0.7%,respectively.The prevenlance rates of thalassaemia in boys and girls were 9.3% and 10.5%,respectively.These was no significant difference between different ages and genders.Conclusion The prevenlance of thalassemia is high among the Han children in Baoshan of Yunnan,and the prevelance rate of G6PD deficiency is lower than before.There is no significant difference in prevenlance rates of thalassaemia between different ages and genders.
出处
《昆明医科大学学报》
CAS
2012年第5期54-56,共3页
Journal of Kunming Medical University
