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基于导模共振效应的自支撑超灵敏生物探测器 被引量:4

High-sensitive Biosensor Based on GMR in Self-suspended Grating
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摘要 基于多层平面波导理论,采用自支撑共振光栅,提出了一种应用于生物探测领域的超高准确度传感器.理论计算表明,本文提出的生物传感器,其探测准确度于共振光栅的周期成正比,接近基于共振效应传感器的理论极限.采用单层共振光栅的归一化色散方程,计算了色散曲线随探测介质折射率的变化关系,从而证明了其探测准确度.此外,基于此共振光栅结构,设计了工作在近红外和中红外波段的生物探测器,分别应用于液体(1.3~1.7)和气体探测,折射率的分辨能力在近红外波段可以达到1×10-5,在红外波段优于1×10-6,能满足绝大多数生物材料的探测.相比于传统的基于导模共振效应的共振传感器,本文提出的生物传感器,其探测准确度有一至两个数量级的提高. A high-sensitive biosensor based on the GMR effect in the self-suspended grating (SSG) is proposed. The calculations demonstrated that the sensitivity of the proposed bio-sensor is near the theoretical limit compared with conventional GMR sensor. Based on the normalized Eigen-function of single layer homogenous grating, the resonance curves with respect to the different refractive indices of surrounding media are calculated, with which confirm the estimated sensitivity. In addition, the highly sensitive bio-sensor in the near and mid IR wavelength region is designed for liquids and gases detection respectively. The sensor can deliver the resolution over 1×10-5 in the near IR region in a large refractive index (1.3~1.7) range and provide better than 1×10-6 in mid IR region, which is enough for various bio-material detections. Therefore, the proposed bio-sensor is one or two order's more sensitive than the conventional GMR sensors.
出处 《光子学报》 EI CAS CSCD 北大核心 2012年第12期1483-1487,共5页 Acta Photonica Sinica
基金 上海市自然科学基金(No.10ZR1433500) 浙江省自然科学基金(No.KYZ074108017资助
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