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结直肠癌肝转移的危险因素分析 被引量:6

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摘要 目的探求影响结直肠癌肝转移的临床病理因素,为其早期诊断、早期治疗提供理论参考。方法选取992例结直肠癌的临床病理资料,根据术前与术中诊断肝转移情况进行统计学分析,探讨患者性别、年龄、肿瘤部位、大小、累及肠管周径、大体类型、组织类型、病理分级、浸润深度、淋巴结转移、盆腹膜种植、Dukes分期、肝外转移、术前血清癌胚抗原(CEA)水平等与肝转移之间的关系。结果 992例结直肠癌,106例在确诊肿瘤时出现肝转移,占10.7%。单因素分析显示,肿瘤部位、大小、病理分级、浸润深度、淋巴结转移、盆腹膜种植、肝外转移、Dukes分期、术前血清CEA水平与肝转移有关(P<0.05)。多因素分析表明,肿瘤部位、淋巴结转移、盆腹膜种植、肝外转移、Dukes分期为影响肝转移的主要因素(P<0.05)。结论结直肠癌肝转移的主要危险因素有肿瘤部位、淋巴结转移、盆腹膜种植、肝外转移、Dukes分期。
出处 《西安交通大学学报(医学版)》 CAS CSCD 北大核心 2012年第4期525-527,共3页 Journal of Xi’an Jiaotong University(Medical Sciences)
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