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骨髓、脐血干细胞中淋巴细胞和单核细胞与CD34、CD38亚型细胞百分比在治疗肝硬化中的比较 被引量:14

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摘要 目的观察骨髓血干细胞和脐带血干细胞在细胞总数中的比例,并分析两者在肝硬化治疗中的作用。方法 50例肝硬化患者行干细胞移植治疗肝硬化,其中34例采用自体骨髓干细胞移植治疗,16例采用脐带血干细胞移植治疗。分析干细胞分离后淋巴细胞和单核细胞的数量及CD34、CD38水平。结果分离后的脐带血淋巴细胞和单核细胞百分比分别为60.56%和17.93%,明显多于骨髓血46.75%和10.70%。分离后脐血干细胞的CD34、CD38明显多于骨髓血干细胞,分别为5.7∶1.6和2.4∶1.6。结论脐带血干细胞所占细胞明显优于骨髓血干细胞中所占细胞的比例,在干细胞治疗肝硬化时,能够提供具有丰富数量及质量的细胞应用于临床。
出处 《中华临床医师杂志(电子版)》 CAS 2011年第6期1731-1733,共3页 Chinese Journal of Clinicians(Electronic Edition)
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参考文献7

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