1Global Initiative for Chronic Obstructive Lung Disease.Workshopreport:global strategy for the diagnosis,management and preventionof COPD. http//goldcopd.org . 2008 被引量：1
2Wise RA,Kanner RE,Lindgren P,et al.The effect of smokingintervention and an inhaled bronchodilator on airways reactivity inCOPD:the lung health study. Chest . 2003 被引量：1
3A L?kke,P Lange,H Scharling,P Fabricius,J Vestbo.Developing COPD: a 25?year follow up study of the general population. Thorax . 2006 被引量：1
4邓伟吾..实用临床呼吸病学[M],2004.
5Motz GT,Eppert BL,Sun G, et al.Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema. J Immunol . 2008 被引量：1
6Cosio M G,Majo J,Cosio M G.Inflammation of the airways and lung parenchyma in COPD:role of T cells. Chest . 2002 被引量：1
2Pauwels RA, Rabe KF. Burden and clinical features of chron obstructive pulmonary disease (COPD). Lancet. 2004;364:613-620. 被引量：1
3Cosio MG, Guerassimov A. Chronic obstructive pulmonary disease. Inflammation of small airways and lung parenchyma. Am J Respir Crit Care Med. 1999:160:S21-25. 被引量：1
4Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol, 2008;8:183-192. 被引量：1
5Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 2003;22:672-688. 被引量：1
6Quint JK, Wedzicha JA. The neutrophil in chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2007;119:1065- 1071. 被引量：1
7Shapiro SD. The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999; 160:529-32. 被引量：1
8Tetley TD. Macrophages and the pathogenesis of COPD. Chest. 2002;121:156S-159S. 被引量：1
9Fletcher C, Peto R. The natural history of chronic airflow obstruction. Br Med J. 1977; 1 : 1645-1648. 被引量：1
10Simmons MS, Connett JE, Nides MA, et al. Smoking reduction and the rate of decline in FEV(I ): results from the Lung Health Study. Eur Respir J. 2005;25:1011-1017. 被引量：1
6Rana JS, Mittleman MA, Sheikh J, et al. Chronic obstructive pulmonary disease, asthma, and" task of type 2 diabetes in women. Diabetes Care,2004,27:2478. 被引量：1
7Karim M, Kingsley CI, BusheU AR, et al. Al|oantigen-induced CD25 + CD4 regulatory T cells can develop in vivo from CD25- CIM precursors in a thymus-independent process. J Immuno1,2004, 172:923-928. 被引量：1
8Jakobsson P, Jorfeldt L, Von schenck H. Insulin resistance is not exhibited by advanced chronic obstructive pulmonary disease patients. Clin Physiol, 1995,15:547-555. 被引量：1
9Annunziato F, Cosmi L, Santarlasci V,et al. Phenotypic and functional features of human Thl7 cells. J Exp Med,2007,204:1849-1861. 被引量：1
10Shen LS, Wang J, Shen DF, et al. CD4 ( + ) CD25 ( + ) CD127 (low/-) regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression. Clin Immuno1,2009,131 : 109-118. 被引量：1
