摘要
目的观察醒脑静和纳洛酮治疗中、重度新生儿缺氧缺血性脑病的疗效。方法对148例患儿入院后24h内测量QT离散度(QTcd)及肌酸激酶同功酶(CK-MB)值;治疗20d后,均用同一方法及同一台机器复查。所有病例均按照“3项支持疗法和3项对症处理”进行常规综合治疗。对照组给予纳洛酮静脉滴注;治疗组在对照组治疗基础上,加用醒脑静注射液静脉滴注。结果2种治疗方法意识恢复时间疗效比较治疗组与对照组有显著差异。2种治疗方法NBNA评分比较观察组与对照组有显著差异,观察组NBNA评分高于对照组。2种治疗方法QTcd及CK-MB值比较,治疗组与对照组有显著差异。结论醒脑静和纳洛酮治疗中、重度新生儿缺氧缺血性脑病疗效显著。
Objective To observe the clinical effect of Xingnaojing combined with naloxone in the treatment of moderate and severe ischemic-hypoxic encephalopathy.Methods At the 24th hour of admission,148 patients's QTcd and CK-MB levels were determined.After 20 days of treatment,the above-mentioned levels were determined again.All the patients were given comprehensive routine treatment according to the principle of “three supporting therapy and three expectant management ”.In the control group,the patients were given ...
出处
《中国中西医结合儿科学》
2007年第2期89-91,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
关键词
新生儿缺氧缺血性脑病
药物疗法
临床对照实验
醒脑静
纳洛酮
Ischemic-hypoxic encephalopathy in the newborn
Drug therapy
Clinical control experiment
Xingnaojing
Naloxone
