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Adsorption of Proteins with Tannin Modified Chitosan Magnetic Particles

Adsorption of Proteins with Tannin Modified Chitosan Magnetic Particles
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摘要 Magnetic polymer particles have been widely used in biochemistry and medicine in recent years [1-4], mainly due to their property of relatively rapid and easy separation. There were many ways for preparation of magnetic particles [5-9]. We know natural polymer having convenient site such as-NH2,-COOH,-OH,-CONH2, etc. for the affinity ligand attachment. The literature reported chitosan as magnetic polymer matrix, dye as affinity ligand to purify bovine serum albumin and lysozyme[10l. Tannin, a natural product having multiple adjacent hydroxy groups, has extremely high affinity to adsorb protein or alkaloid. However, the information about tannin modified magnetic support is still sparse. Therefore, tannin modified chitosan magnetic particle was prepared and the adsorption of trypsin and aprotinin were studied.
作者 CHANG Yue
出处 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2001年第z1期182-183,共2页 高等学校化学研究(英文版)
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