摘要
目的探讨浆膜腔积液脱落细胞学、肿瘤标志物检测、肿瘤细胞培养和染色体检查分析在恶性肿瘤诊断中的灵敏性和特异性。方法浆膜腔积液采用脑脊液细胞学玻片离心法制片,迈-格-姬染色、丫啶橙荧光染色、部分标本行高碘-雪夫染色(PAS)后观察。部分标本分别进行了肿瘤细胞培养、肿瘤标志物检测及染色体检查分析。结果 78例恶性肿瘤浆膜腔积液中腺癌45例、鳞癌14例、未分化癌8例、白血病5例、恶性淋巴瘤3例、间皮细胞瘤2例、神经母细胞瘤1例。结论浆膜腔积液脱落细胞学检查结合肿瘤细胞培养、肿瘤标志物检测和染色体检查分析是诊断恶性肿瘤的重要手段。
Objective To study the sensibility and differential of serous cavity effusion cytology,tumor maker,tumor cell culture and chromosome in diagnosing malignant tumor.Methods Serous cavity effusion were tested by CSF centrifuge,May-Grunwald-Giemsa,AO,and parts of PAS staining while tumor cell culture,tumor maker and tumor chromosome were analysis in some of specimen.Results In all 78 cases of malignant tumor specimen,we found 45 were adenocarcinoma,14 were squamous cell carcinoma,8 were undifferentiated carcinoma,5 were leukemia and 3 were malignant lymphoma,et al.Conclusion Combined with tumor cell culture,tumor maker,and tumor chromosome analysis,serous cavity effusion cytology plays an important role in diagnosis of malignant tumor.
出处
《脑与神经疾病杂志》
2010年第5期368-370,共3页
Journal of Brain and Nervous Diseases
关键词
浆膜腔积液
恶性肿瘤
脱落细胞学
诊断
Serous cavity effusion
Malignant tumor
Effusion
Cytology diagnosis
