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重症急性胰腺炎早期液体复苏的临床研究 被引量:3

Strategy of Fluid Resuscitation in the Early Stage of Severe Acute Pancreatitis
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摘要 目的:探讨急性重症胰腺炎(SAP)早期不同种类液体复苏对其预后的影响。方法:应用随机对照的方法,分别对2007年12月~2009年10月同期入院的48例SAP患者,随机分成两组,试验组和对照组。试验组第一周内液体复苏采用晶体液和人工胶体(羟乙基淀粉),对照组采用晶体液,其他治疗方法不变。然后统计其第一周死亡率、ARDS、多器官功能障碍综合征(MODS)发生率,对比两组患者呼吸频率、血氧饱和度和红细胞压积(HCT)差异,以及两组患者肠功能恢复时间、住院时间以及并发症发生率。结果:试验组的液体复苏较对照组显著改善SAP的各项指标(P<0.05)。血清乳酸水平(1.5±0.5)mmol/L,红细胞压积(HCT)为(32.4±6.9)%,ScvO2为(81.7±15.2)%,病死率8.3%,MODS发生率33.3%,结论:SAP早期联合应用晶胶体进行液体复苏可有效恢复循环血容量和防止体液潴留,显著提高其治愈率。 Objective: To investigate the optimal strategy of fluid resuscitation in the early stage of severe acute pancreatitis.Methods:Fourfy-eighs SAP patients who received treatment in our hospital from 12,2007 to 10,2009 were randomly divided into 2 groups(n=24) according to the different amounts of crystal and colloid in the daily resuscitation,including crystal group,combined group(the ratio of crystal to colloid was 2 to 1).The levels of hematocrit(HCT),saturation of central vein oxygen(ScvO2),serum lactic aci...
出处 《华西医学》 CAS 2009年第12期3121-3123,共3页 West China Medical Journal
关键词 胰腺炎 急性坏死性 液体治疗 pancreatitis acute necrotizing fluid therapy
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参考文献5

  • 1SAUVEN P,PLAYFORTH MJ,EVANS M,et al.Fluid seques-tration:an earlyindicator of mortalityin acute pancreatitis[].British Journal of Surgery.1986 被引量:1
  • 2Ranson JH,Rifkind KM,Rose D,et al.Prognostic signs and the role of operative management in acute pancreatitis[].Surgery Gynecology and Obstetrics.1974 被引量:1
  • 3Ranson,JH,Rifkind,KM,Turner,JW.Prognostic signs and nonoperative peritoneal lavage in acute pancreatitis[].Surgery Gynecology and Obstetrics.1976 被引量:1
  • 4Mark A. Malangoni M.D. and Adam S. Martin M.D.Outcome of severe acute pancreatitis[].The American Journal of Surgery.2005 被引量:1
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