摘要
目的调查佛山市献血人群人类嗜T淋巴细胞白血病病毒I(HTLV-I)的感染状况。方法分别按地区及职业分组。用酶联免疫吸附试验方法(ELISA)筛查2006~2007年佛山市地区的献血人群血清标本26608份。双孔试验确认阳性者采用免疫印迹法(WB)进行确证。结果献血人群中HTLV-I抗体阳性率为0.03%,本地组未检出阳性,而外来组人群检出33例确认阳性,确证阳性为9例,占该组0.05%,两组存在显著性差异(p<0.05)。固定职业组和学生组未检出阳性,而不固定职业组人群检出确认阳性33例,确证阳性为9例,占该组0.05%,与其它两组存在显著性差异(p<0.05)。结论提示在佛山市地区HTLV-I的流行水平很低。不同地区及职业分布可能是影响其流行的一个因素。
Objective To investigate the human T-cell leukaemia virus type Ⅰ(HTLV-I)infective situation of blood donors in Foshan city.Methods 26608 donors in Foshan city were divided into 2 groups by region and 3 groups by occupation during June 2006 to December 2007.They were screened by ELISA for HTLV-I antibody,The positive samples were confirmed through Western blot(WB).Results The positive rate of the donors were 0.03%.In the region groups,the positive rate of the local group had not been found HTLV-I.The positive rate of the other regions group was 0.05%.The positive rate of the local group was significant lower than other regions group(p<0.05).And the no-fixed occupational group was significant high than the fixed occupational group and the student group(p<0.05).Conclusion The sero-prevalence of HLTV-I is very low level in Foshan city.Region and occupation maybe are epidemiological factors.
出处
《医学检验与临床》
2008年第3期77-78,共2页
Medical Laboratory Science and Clinics