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自体脾组织移植的研究 被引量:3

Study on the Autotransplantation of Spleen tissue
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摘要 目的 探索自体脾组织移植在严重脾外伤及门脉高压等全脾切除术病人中应用的可行性及价值。方法 将切除的脾脏 ,除去被膜 ,切成 1cm× 1cm× 0 .5cm的薄片 5 0块 ,移植在大网膜中间 ,用丝线缝合后固定于脾床。结果 经动物试验及术后B超 ,同位素扫描 (99m锝 )随访观察 ,移植的脾组织成活良好。血常规 ,血小板 ,IgM ,IgG ,补体C3,术后从低水平逐渐上升至正常。结论 全脾切除后自体脾组织移植能够成活并增生变大 ,而且能够维持一定的免疫功能 ,可预防严重的全身性感染发生。 Objective To explore the possibility and value of the autotransplantation of spleen tissues in severe spleen injury or portal hypertension to resect the whole spleen. Method The spleen resected was rid of its capsule, cut into 50 masses of 1 cm×1 cm×0.5 cm, put into a big omentum, sewed up with silk suture and fixed in the spleen bed. Result Through animal experiment, utrasonic examination, isotope canning and follow up, the transplanted spleen survived very well. The level of blood routine, platelets, IgM, IgG and Complement C 3 went up to normal after operation. Conclusion After the whole spleen was resected the autografting of spleen can survive, get large, maintain certain immune function and prevent severe general infection.
作者 苟永禧
出处 《临床军医杂志》 CAS 2000年第4期29-30,共2页 Clinical Journal of Medical Officers
关键词 自体脾移植 实验研究 临床应用 autotransplantation of spleen experimental study clinical applicat
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同被引文献46

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