摘要
目的 观察吉西他滨联合顺铂治疗晚期非小细胞肺癌临床疗效及不良反应。方法 4 6例患者采用吉西他滨 1g m2 ,d1,8,15及顺铂 90mg m2 分两天 (d 2 ,3)化疗。 2 8天为 1周期 ,3周期评价疗效。结果 4 6例可评价疗效和不良反应。初治病例RR 5 3 8% ;复治病例 35 %。主要不良反应为骨髓抑制。结论 吉西他滨联合顺铂治疗晚期非小细胞肺癌有效率较高 。
Objective To evaluate the curative effect and toxicity of gemcitabine combined with cisplatine in treatment advance of non-small-cell lung cancer.Methods 46 cases were treated with gemcitabine 1g/m 2 iv d1,8,15,and cisplatine 90mg/m 2 iv d 2,3,repeated every 4 weeks and the clinical response was assesed after three cycles.Results It shows that effective rate of primary treatment was 53.8%,effective rate of re treatment was 35.0%.The principal toxicity was inhibition of bone marrow.Conclusion Gemcitabine combined with cisplatine shows a better theraputic effect in treatment of advanced non-small cell lung cancer,and toxic side-effect are tolerant.
出处
《癌症进展》
2004年第4期285-287,共3页
Oncology Progress
关键词
非小细胞肺癌
吉西他滨
顺铂
联合化疗
non-small cell lung cancer gemcitabine cisplatine combined chemotherapy
