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吗啡单次注入硬膜外腔剖宫产术后镇痛的临床观察 被引量:3

Clinical assessment of single-dose epidural infusion of morphine in postoperative analgesia
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摘要 目的探讨吗啡单次注入硬膜外腔对剖宫产术后镇痛的效果。方法360例剖宫产产妇随机分为3组,每组各120例。Ⅰ组术毕单次吗啡5mg注入硬膜外腔,Ⅱ组术毕与硬膜外导管连接设置好的PCEA装置(5mg吗啡加生理盐水至100ml),Ⅲ组术毕不使用任何药物。结果Ⅰ、Ⅱ组术后无明显疼痛感,镇痛效果良好,两组比较差异无显著性(P>0.05),而Ⅲ组患者则有明显的术后疼痛感。Ⅰ组患者的术后肠蠕动完全恢复时间明显快于Ⅱ组,两组比较差异有显著性(P<0.01)。Ⅰ、Ⅱ组患者产后出血、子宫复旧、泌乳情况比较,差异均无显著性(P>0.05)。结论单次吗啡注射完全能达到PCEA的镇痛效果,且方法简单,适合推广使用。 Objective To investigate the effects of single-dose epidural infusion of morphine in patients of postcesarean section. Methods 360 pregnant women were randomly divided into three groups.GroupⅠ, 5mg morphine was injected into the epidural space after cesarean section. GroupⅡ,5mg morphine mixed fluid (0.005%100ml)was injected into patients by PCEA for postoperative analgesia. GroupⅢ, nothing was injected . Results overall patients in groupⅠ and Ⅱwere satisfied with the postoperative analgesia. The recovery of bowel movement in groupⅠ (19.0±5.2) h was much buffer than in groupⅡ (30.0±4.1) h (P<0.01).There were no remarkerble differences between groupⅠand Ⅱin the incidence of postpartum hemorrrahage ,lactation and recovery of uterus. Conclusions Both single-dose epidural infusion of morphine and PCEA have excellent analgesic effect, but single-dose epidural infusion of morphine is much more simple and effective than PCEA in patients of postcesarean section. This will be a new strategy of postoperative analgesia.
出处 《中国医药导报》 CAS 2006年第29期84-85,共2页 China Medical Herald
关键词 吗啡 镇痛 硬膜外 剖宫产 morphine analgesia, epidural cesarean section
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