摘要
观察杀虫丁对小鼠免疫系统的影响,以白细胞总数、免疫器官脏器系数、血清溶血素水平、迟发超 敏足垫肿胀率及碳粒廓清指数为指标。连续天灌胃给药,、剂量,未见对免疫功能的280.2 mg/kg2.0 mg/kg 明显影响,在剂量,可见血清溶血素水平明显降低,表明杀虫丁在该剂量亚慢性染毒条件下对小鼠20 mg/kg体液免疫功能有显著性抑制作用,而对小鼠细胞免疫功能未观察到有明显作用。
Objects]To investigate the effects of shachongding with sub-chronic exposure on immune function in mice. [Methods] The mice were properly treated in 28 d . WBC. immune organ weight coefficient, serum hemolysin, incidence of footpad swell and clearance of charcoal particles were determined respectively. [Results] Compared with the control, the level of serum hemolysin reduced significantly at 20 mg/kg/d SHACHONGDING; however, other immune functions were not changed markedly. [Conclusion] shachongding at 20 mg/kg/d for 28d could inhibit humoral immune function.
出处
《湖北职业技术学院学报》
2002年第2期69-71,共3页
Journal of Hubei Polytechnic Institute
