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树突状细胞的免疫治疗进展 被引量:2

Development of immunotherapy based on dendritic cell
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摘要 树突状细胞 (DC)是体内专职的抗原提呈细胞 ,具有摄取、处理和呈递抗原至 T细胞的功能 ,这一过程需要MHC分子参与 ,结合于 MHC上的抗原多肽由不同的 T细胞亚群所识别。将肿瘤相关抗原 (TAA)致敏 DC后 ,回输或接种至荷瘤宿主能显著地诱导机体产生保护性免疫反应。许多 TAA在分子水平上的确认以及对 DC抗原提呈作用的深入研究 ,使以DC为基础的肿瘤免疫治疗具有发展前景。
出处 《免疫学杂志》 CAS CSCD 北大核心 2000年第z1期70-71,74,共3页 Immunological Journal
基金 重庆市院士基金
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