摘要
目的观察不同剂量的丙种球蛋白对川崎病患儿冠状动脉损害的预防作用。方法将我院收治的93例川崎病患儿按治疗方法分成两组,A组患儿给予静脉注射丙种球蛋白400 mg·kg-1·d-1,连用5 d;B组患儿给予静脉注射丙种球蛋白1 000 mg·kg-1·d-1,连用2 d;且两组患儿均口服阿司匹林30～50 mg·kg-1·d-1。住院观察2～3周,行超声心动图检查,比较两组患儿症状缓解情况和冠状动脉损害发生率。结果两组患儿治疗后退热时间、发热时间、住院时间及冠状动脉损害发生率比较,差异均有统计学意义(P<0.05)。结论在缓解症状、缩短发热时间及降低冠状动脉损害的发生率方面,两日大剂量丙种球蛋白联合阿司匹林治疗优于五日小剂量丙种球蛋白联合阿司匹林治疗。
Objective To compare the effects of different dosages of intravenous gamma globulin(IVGG) in treating Kawasaki disease(KD).Methods A retrospective review was carried out on the medical records of KD patients at our institution from February 2002 to February 2008.The patients were divided into two group.Group A were given IVGG,400 mg·kg-1·d-1,5 days,Group B given 1 000 mg·kg-1·d-1,2 days,and both given additional oral aspirin,30～50 mg·kg-1·d-1.After 2～3-week observation,ultrasound cardiogram was performed to...
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第6期493-495,共3页
Chinese General Practice
