摘要
目的探测心肌炎患儿呼吸道分泌物中的病毒表达以及与心脏功能的关系。方法选择符合临床诊断心肌炎的31例患儿,取患儿气管分泌物,采用分子技术探测呼吸道分泌物病毒表达,同时测患儿心肌酶(CK-MB)、肌钙蛋白(CTnI)、血常规、C反应蛋白(CRP)及心脏彩色多普勒检查。比较患儿病毒感染检测发生率与心肌酶变化、心功能之间关系。结果15例(48. 4%)患儿检测出病毒,其中肠道病毒检出率56.5%.病毒检测阳性组和阴性组的心肌酶谱CK-MB(U/L)分别为25.8±13.5,16.5±8.6(P<0.05);肌钙蛋白CTnI(μg/L)分别为1.15±0.87,0.76±0.68(P<0.05);左室射血分数LVEF(%)分别为49.11±18. 90,64.61±18.78(P<0.05)。结论临床诊断心肌炎患儿与肠道病毒感染有关;病毒检测阳性组较检测阴性组患儿心肌损害明显,心脏收缩功能降低。
Objective To investigate the relationship between viral detection in tracheal aspirates(TA)from children with myocarditis and cardiac function.Methods To detect the expression of viral in TAs from 31 children(22males/9females)with who diagnosed as myocarditis by using molecular techniques;The blood routine and the levels of serum cardiac troponinⅠ(CTnI),CK-MB,blood routine,C reactive protein(CRP)were detected.Their heart Doppler echocardiography were obtained;then compaired cardiac function of children betw...
出处
《潍坊医学院学报》
2008年第6期-,共2页
Acta Academiae Medicinae Weifang
关键词
心肌炎
病毒检测
心功能
Myocarditis
Viral detection
Heart function tests
