摘要
建立HPLC法测定头孢克洛干混悬剂中的有关物质。色谱柱为Hypersil C18BDS柱,流动相A为0.78%磷酸二氢钠溶液(pH4.0),流动相B为0.78%磷酸二氢钠溶液-乙腈(体积比为55:45),流速为1mL/min,检测波长为220nm。该方法测定结果的相对标准偏差为0.01%(n=6),标示样品测定结果的相对误差不大于1.0%,可满足企业质量控制的检测要求。
A HPLC method for the determination in relevant substances of cefaclor suspension was established with Hypersil C18 BDS column.The mobile phase A was 0.78% sodium dihydrogen phosphate solution(pH 4.0).The mobile phase B was 0.78% sodium dihydrogen phosphate solution-acetonitrile(volume ratio was 55:45),with flow rate of 1 mL/min.The detection wave lenth was at 220 nm.The relative standard deviation of detection results was 0.01%(n=6).The relative error of marker specimen detection results was not more than ...
出处
《化学分析计量》
CAS
2009年第1期42-45,共4页
Chemical Analysis And Meterage
